The geopolitical dynamics of Southeast Asia in the post-pandemic era reflect various challenges and opportunities. As a strategic region, Southeast Asia is a meeting point of global interests, especially between major powers such as the United States and China. Rising tensions in the South China Sea, for example, show how regional countries must navigate between economic interdependence and national security. In the economic context, Southeast Asian countries are starting to recover after experiencing a significant impact from the COVID-19 pandemic. Countries such as Vietnam and Indonesia are projecting strong growth, with a focus on digitalization and industrial innovation. Initiatives such as RCEP (Regional Comprehensive Economic Partnership) play a role in strengthening economic cooperation between countries, which in turn facilitates mutual recovery. Furthermore, environmental issues are also increasingly dominating the geopolitical agenda. Climate change, with its higher risk of natural disasters, is pushing countries in Southeast Asia to work together on mitigation and adaptation. Cooperation in the management of water resources and renewable energy is the main focus, where foreign investment is directed towards creating sustainable energy sources. On the political side, there has been a significant shift in power dynamics. The emergence of new, progressive leaders has the potential to change foreign policy. By prioritizing diplomacy, these countries are trying to build good relations with global competition, reduce long-standing political tensions and contribute to regional stability. The role of ASEAN (Association of Southeast Asian Nations) is also increasingly important. This organization seeks to strengthen solidarity between its member countries in dealing with various regional issues, including security and health issues. Consensus and dialogue are the keys to reaching agreement, even though they often have to face differences in views among their members. Geopolitical interests in this region are also influenced by technological developments. The industrial revolution 4.0 driven by digitalization is affecting the way countries interact with each other. Cooperation in the information and communication technology sector is very vital, considering the role of technology in increasing the country’s competitiveness. Ultimately, the biggest challenge for Southeast Asian countries in the post-pandemic era is creating inclusive and sustainable policies. Given the existing vulnerabilities, it is critical to involve civil society in decision making. This will not only strengthen democracy, but also ensure that the recovery process is fair and equitable. In a broader context, the geopolitical dynamics of post-pandemic Southeast Asia suggest that collaboration between countries and adaptation to change are very necessary. By focusing on economic integration, security and sustainable development, the region can build a solid foundation for the future.